186 lines
5.9 KiB
Markdown
186 lines
5.9 KiB
Markdown
# 医疗制药搜索规则
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## 1. 核心原则
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- **语言优先**：默认英文搜索，医学科研以英文为国际标准
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- **权威优先**：政府监管机构 > 医学期刊 > 制药公司官方 > 专业媒体
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## 2. 英文权威信息源库
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### 2.1 政府监管机构（最高优先级）
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- **美国**：
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- FDA: https://www.fda.gov
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- CDC: https://www.cdc.gov
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- NIH: https://www.nih.gov
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- CMS: https://www.cms.gov
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- **欧洲**：
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- EMA: https://www.ema.europa.eu
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- WHO Europe: https://www.who.int/europe
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- ECDC: https://www.ecdc.europa.eu
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- **英国**：
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- MHRA: https://www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency
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- NHS: https://www.nhs.uk
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- **国际组织**：
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- WHO: https://www.who.int
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- WIPO: https://www.wipo.int (医药专利)
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### 2.2 顶级医学期刊
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- **综合医学**：
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- New England Journal of Medicine: https://www.nejm.org
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- The Lancet: https://www.thelancet.com
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- JAMA Network: https://jamanetwork.com
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- BMJ: https://www.bmj.com
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- **专科期刊**：
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- Nature Medicine: https://www.nature.com/nm
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- Science Medicine: https://www.science.org/medicine
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- **药学期刊**：
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- Pharmaceutical Journal: https://pharmaceutical-journal.com
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- Drug Topics: https://www.drugtopics.com
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### 2.3 学术与研究平台
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- **PubMed**: https://pubmed.ncbi.nlm.nih.gov
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- **Cochrane Library**: https://www.cochranelibrary.com
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- **ClinicalTrials.gov**: https://www.clinicaltrials.gov
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- **PLoS Medicine**: https://journals.plos.org/plosmedicine
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### 2.4 头部制药公司官方
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- **Big Pharma**：
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- Pfizer: https://www.pfizer.com
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- Johnson & Johnson: https://www.jnj.com
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- Roche: https://www.roche.com
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- Novartis: https://www.novartis.com
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- **生物技术**：
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- Genentech: https://www.gene.com
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- Amgen: https://www.amgen.com
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- Gilead: https://www.gilead.com
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- Biogen: https://www.biogen.com
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- **疫苗公司**：
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- Moderna: https://www.modernatx.com
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- BioNTech: https://biontech.de
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## 3. 专业医疗媒体与KOL
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### 3.1 权威医疗媒体
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- **专业媒体**：
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- Medscape: https://www.medscape.com
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- WebMD: https://www.webmd.com
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- Healthline: https://www.healthline.com
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- **行业媒体**：
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- FiercePharma: https://www.fiercepharma.com
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- BioPharma Dive: https://www.biopharmadive.com
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- STAT News: https://www.statnews.com
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- **投资分析**：
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- Evaluate: https://www.evaluate.com
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- GlobalData Healthcare: https://www.globaldata.com/healthcare
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### 3.2 医学专家与KOL Twitter
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- **FDA官员**：
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- @SteveFDA: https://twitter.com/SteveFDA
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- @DrWoodcockFDA: https://twitter.com/DrWoodcockFDA
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- **知名医生**：
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- @drericding: https://twitter.com/drericding
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- @celinegounder: https://twitter.com/celinegounder
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- **研究专家**：关注各领域顶级研究者
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- **制药高管**：主要制药公司CEO/CSO
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### 3.3 专业论坛与社区
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- **Reddit医学**：
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- Medicine: https://www.reddit.com/r/medicine
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- Pharmacy: https://www.reddit.com/r/pharmacy
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- Biotech: https://www.reddit.com/r/biotech
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- **专业论坛**：
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- Student Doctor Network: https://forums.studentdoctor.net
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- AllNurses: https://allnurses.com
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- **LinkedIn群组**：Pharmaceutical Industry Professionals
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## 4. 搜索策略与关键词
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### 4.1 药物研发搜索
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**关键词模板**：
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- "[drug name] clinical trial [phase] [year]"
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- "FDA approval [therapeutic area] [date]"
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- "[disease] treatment breakthrough [year]"
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- "biomarker [condition] research [period]"
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### 4.2 监管政策搜索
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**关键词模板**：
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- "FDA guidance [therapeutic area] [year]"
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- "drug regulation [country] [topic]"
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- "clinical trial regulations [region]"
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- "pharmaceutical compliance [area]"
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### 4.3 市场分析搜索
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**关键词模板**：
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- "pharmaceutical market [therapeutic area] [year]"
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- "drug pricing [country] [policy]"
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- "biosimilar competition [drug class]"
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- "orphan drug [indication] [market]"
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### 4.4 医疗技术搜索
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**关键词模板**：
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- "digital health [technology] [application]"
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- "AI medical diagnosis [specialty]"
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- "telemedicine adoption [region] [year]"
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- "medical device innovation [area]"
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## 5. 行业专门搜索网站
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### 5.1 药物开发数据库
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- **DrugBank**: https://go.drugbank.com
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- **Drugs@FDA**: https://www.accessdata.fda.gov/scripts/cder/daf
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- **EMA Database**: https://www.ema.europa.eu/en/medicines
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- **PharmaProjects**: https://pharmaprojects.com
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### 5.2 临床试验平台
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- **ClinicalTrials.gov**: https://www.clinicaltrials.gov
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- **WHO ICTRP**: https://trialsearch.who.int
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- **EudraCT**: https://eudract.ema.europa.eu
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### 5.3 医疗投资与分析
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- **BioCentury**: https://www.biocentury.com
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- **Nature Biotechnology**: https://www.nature.com/nbt
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- **Genetic Engineering News**: https://www.genengnews.com
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## 6. 实时监控重点
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### 6.1 高频监控（每日）
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- FDA批准公告
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- 临床试验结果发布
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- 药物安全警告
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- 主要制药公司新闻
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### 6.2 中频监控（每周）
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- 新药申请状态
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- 监管指导文件更新
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- 医学会议摘要
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- 投资并购动态
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### 6.3 低频监控（每月）
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- 行业趋势报告
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- 长期临床试验进展
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- 政策法规修订
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## 7. 文件命名与归档
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### 7.1 命名规则
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- **药物研发**：`YYYYMMDD_Pharma_Drug_[DrugName/Indication].docx`
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- **监管政策**：`YYYYMMDD_Pharma_Regulation_[Topic/Agency].docx`
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- **医疗技术**：`YYYYMMDD_Pharma_Tech_[Technology/Device].docx`
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- **市场分析**：`YYYYMMDD_Pharma_Market_[TherapeuticArea].docx`
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### 7.2 内容格式
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**文档头部**：
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- Source: [完整URL链接]
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- Keywords: [Medical terms used]
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- Search Time: [YYYY-MM-DD HH:MM UTC]
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- Therapeutic Area: [Oncology/Cardiology/etc.]
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- Development Stage: [Preclinical/Phase I-III/Approved]
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## 8. 中国特定搜索（仅当明确要求时）
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### 8.1 中国医药监管
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- NMPA(药监局): https://www.nmpa.gov.cn
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- 卫健委: http://www.nhc.gov.cn
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- 中检院: http://nifdc.org.cn
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### 8.2 中文关键词
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- "药物研发"、"临床试验"、"药品审批"、"医疗器械" |